Omega-3 fatty acids (EPA · DHA) + brain atrophy inhibitory effect of vitamin B group

Specialized journal (electronic version) of the month of clinical nutrition, in the omega-3 fatty acids (EPA · DHA) is high, clinical studies showed brain atrophy inhibitory effect of combined administration of vitamin B group, from the European group It had been reported. (Am J Clin Nutr. 2015 Apr 15.) Blood omega-3 essential fatty acid and homocysteine ​​levels and, associated with brain atrophy and dementia have been suggested. In this study, In progress inhibitory effect of vitamin B group administration to brain atrophy, Impact of blood omega-3 fatty acids (EPA · DHA) value has been verified. (It is part of the research that VITACOG.) In particular, As randomized controlled trials, To target more than 70-year-old of the elderly 168 people with mild cognitive impairment, And high-dose vitamin B-treated group (n = 85) (Folic acid per day; 0.8 mg, vitamin B 6; 20 mg, vitamin B12; 0.5 mg) -Placebo group (n = 83) Targeting, Evaluation of brain atrophy by MRI is, And it is performed after the start time and two years, It was measured at the time of the start of the test, at tertile of blood levels of omega-3 essential fatty acids, Stratified analysis have been made. As a result of the analysis, With respect to brain atrophy rate, Vitamin B group and the administration, A significant correlation was found between blood omega-3 essential fatty acids value. (P = 0.024) At the start of vitamin B group the administration of the test start time / high dose, The blood group omega-3 essential fatty acids value was high (> 590 μmol / L), By B vitamins administration, As compared to the placebo group, Rate of brain atrophy is that had been 40% inhibition. (P = 0.023) on the other hand, In the group blood omega-3 essential fatty acids value is low (<390 μmol / L), Significant effects of vitamin B group administration was not observed. At the start of the study at the start / administration, blood omega-3 essential fatty acid value (EPA value, DHA value) in the group was the highs, By B vitamins administration, Although rate of progression of brain atrophy was significantly suppressed, The effect in the placebo group was not observed. From the above data, Brain atrophy inhibitory effect of B vitamins administration of high doses, that blood omega-3 essential fatty acids (EPA, DHA) is found in the case is high, Therefore, To brain atrophy suppression by omega-3 essential fatty acids, that high doses of vitamin B group is required, There will be suggested. Among the functional food supplement, the by human clinical studies, has been shown to dementia improvement action is the next component. - Ginkgo biloba extract Symptom improvement effect of dementia by ginkgo biloba extract formulation The dementia improvement effect of Ginkgo biloba extract @ Germany Efficacy and safety of ginkgo biloba extract The cognitive decline inhibitory effect by ginkgo biloba extract 20-year intake · PS (phosphatidylserine) supplements Cognitive function improving action by the PS (phosphatidylserine) Extra virgin (virgin) olive oil The dementia prevention effect of extra virgin olive oil Vitamin B group Brain atrophy due to vitamin B group administration (gray matter atrophy) inhibitory effect and cognitive decline inhibitory effect Clinical studies showed brain atrophy progression inhibitory effect Generally, when to expect the effect on cognitive function, B vitamins, omega-3 fatty acids (EPA and DHA), it necessary to use a relatively long period supplements such Ginkgo biloba extract (over several months) I thought you. In addition, dementia improvement action by turmeric, curcumin has also been reported. In DHC, also it has a product of complex supplements.