Cognitive by PQQ dysfunction inhibitory effect

Professional journal of the month of brain science research, had been reported basic research shows the neuroprotective effect of PQQ. (Behav Brain Res 2014 Jan 1; 258:. 153-9) Vitamin which is one PQQ (pyrroloquinoline quinone) of (like substance) is, and energy metabolism in the mitochondria, from a role in nerve function, Function to cognitive function has been suggested, Currently, the function of the brain as food has been appeal. In previous research, It has been suggested that PQQ binds to the NMDA receptor. In this study, Action by the PQQ in neurocognitive impairment has been verified. In particular, MK-801-induced abnormal behavior is a model of schizophrenia, in cognitive impairment model mouse, MK-801 (0.5mg / kg / d) When PQQ (0.2, 2.0, or 20 μg / kg / d) But 60 days, it is administered, Motor nerve capacity, have been made to evaluate, such as cognitive function test. As a result of the analysis, By PQQ administration, Behavioral abnormalities and ataxia of MK-801 induced significantly suppressed, Protective effect against neurological disorders and mental psychological behavioral abnormality is that has been suggested. In the future, it is the field of verification of clinical significance is expected. With respect to PQQ, subsequent studies have been reported. Anti-inflammatory effect of PQQ (pyrroloquinoline quinone): human clinical research Cognitive function maintenance effect of PQQ (pyrroloquinoline quinone)