The effect of improving the storage ability in diabetes reserve army with turmeric

Professional journal of the month of clinical nutrition, in diabetes reserve army, clinical studies had been reported from a group of Taiwan that showed the effect of improving the storage ability of turmeric administration. (Asia Pac J Clin Nutr 2014; 23 (4):. 581-91.) It is known that blood sugar levels increase the risk of high and dementia, Dementia measures as a complication of diabetes are required. In this study, In diabetes reserve army, Impact on cognitive function by turmeric and cinnamon have been verified. In addition, cinnamon, in previous studies, has been shown glycemic control improvement action, Turmeric / curcumin has been shown to dementia risk reduction action. In particular As a double-blind, placebo-controlled trial, In the subject for more than 60 years of diabetes reserve army patients 48 people, (Subjects newly diagnosed, untreated patients) - Turmeric (1g) administration group, Cinnamon (2g) administration group, - Turmeric 1g + cinnamon 2g combined administration group, There, along with the breakfast of white bread (119g), has been administered Before and after administration, Storage capacity (working memory), Sugar metabolism-related indicators, such as blood sugar and insulin levels, Including the level of the amyloid precursor is indicative of Alzheimer's disease are measured. As a result of the analysis, Working memory, which is an index of the storage capacity, In turmeric administration group, In score of 3.0, it is that it was raised from 2.6 to 2.9 (improvement). (P = 0.05) No significant change in the cinnamon-treated group, Synergy with the combination did not even observed. Improvement of working memory, Significant negative correlation with insulin resistance has been found. (R = -0.418, p <0.01) It should be noted, it does not have significant changes shown in the Alzheimer's related indicators. From the above data, In diabetes reserve army, Cognitive function improving action by turmeric administration is suggested. In the future, it is the field of verification of clinical significance is expected. Among the functional food supplement, the by human clinical studies, has been shown to dementia improvement action is the next component. Effect on dementia by Ginkgo biloba extract: meta-analysis Ginkgo leaf extract Symptom improvement effect of dementia by ginkgo biloba extract formulation The dementia improvement effect of Ginkgo biloba extract @ Germany Efficacy and safety of ginkgo biloba extract The cognitive decline inhibitory effect by ginkgo biloba extract 20-year intake Synergy and ginkgo leaf extract of dementia treatment PS (phosphatidylserine) supplements Cognitive function improving action by the PS (phosphatidylserine) Extra virgin (virgin) olive oil The dementia prevention effect of extra virgin olive oil The cognitive function improvement by soy isoflavone effect @ meta-analysis Vitamin B group Brain atrophy due to vitamin B group administration (gray matter atrophy) inhibitory effect and cognitive decline inhibitory effect Clinical studies showed brain atrophy progression inhibitory effect The effect to suppress the progress of Alzheimer's disease by omega-3 essential fatty acids and α-lipoic acid Generally, when to expect the effect on cognitive function, B vitamins, omega-3 fatty acids (EPA and DHA), it necessary to use a relatively long period supplements such Ginkgo biloba extract (over several months) I thought you. In addition, dementia improvement action by turmeric, curcumin has also been reported. In DHC, also it has a product of complex supplements.

Omega-3 fatty acids (EPA · DHA) + brain atrophy inhibitory effect of vitamin B group

Specialized journal (electronic version) of the month of clinical nutrition, in the omega-3 fatty acids (EPA · DHA) is high, clinical studies showed brain atrophy inhibitory effect of combined administration of vitamin B group, from the European group It had been reported. (Am J Clin Nutr. 2015 Apr 15.) Blood omega-3 essential fatty acid and homocysteine ​​levels and, associated with brain atrophy and dementia have been suggested. In this study, In progress inhibitory effect of vitamin B group administration to brain atrophy, Impact of blood omega-3 fatty acids (EPA · DHA) value has been verified. (It is part of the research that VITACOG.) In particular, As randomized controlled trials, To target more than 70-year-old of the elderly 168 people with mild cognitive impairment, And high-dose vitamin B-treated group (n = 85) (Folic acid per day; 0.8 mg, vitamin B 6; 20 mg, vitamin B12; 0.5 mg) -Placebo group (n = 83) Targeting, Evaluation of brain atrophy by MRI is, And it is performed after the start time and two years, It was measured at the time of the start of the test, at tertile of blood levels of omega-3 essential fatty acids, Stratified analysis have been made. As a result of the analysis, With respect to brain atrophy rate, Vitamin B group and the administration, A significant correlation was found between blood omega-3 essential fatty acids value. (P = 0.024) At the start of vitamin B group the administration of the test start time / high dose, The blood group omega-3 essential fatty acids value was high (> 590 μmol / L), By B vitamins administration, As compared to the placebo group, Rate of brain atrophy is that had been 40% inhibition. (P = 0.023) on the other hand, In the group blood omega-3 essential fatty acids value is low (<390 μmol / L), Significant effects of vitamin B group administration was not observed. At the start of the study at the start / administration, blood omega-3 essential fatty acid value (EPA value, DHA value) in the group was the highs, By B vitamins administration, Although rate of progression of brain atrophy was significantly suppressed, The effect in the placebo group was not observed. From the above data, Brain atrophy inhibitory effect of B vitamins administration of high doses, that blood omega-3 essential fatty acids (EPA, DHA) is found in the case is high, Therefore, To brain atrophy suppression by omega-3 essential fatty acids, that high doses of vitamin B group is required, There will be suggested. Among the functional food supplement, the by human clinical studies, has been shown to dementia improvement action is the next component. - Ginkgo biloba extract Symptom improvement effect of dementia by ginkgo biloba extract formulation The dementia improvement effect of Ginkgo biloba extract @ Germany Efficacy and safety of ginkgo biloba extract The cognitive decline inhibitory effect by ginkgo biloba extract 20-year intake · PS (phosphatidylserine) supplements Cognitive function improving action by the PS (phosphatidylserine) Extra virgin (virgin) olive oil The dementia prevention effect of extra virgin olive oil Vitamin B group Brain atrophy due to vitamin B group administration (gray matter atrophy) inhibitory effect and cognitive decline inhibitory effect Clinical studies showed brain atrophy progression inhibitory effect Generally, when to expect the effect on cognitive function, B vitamins, omega-3 fatty acids (EPA and DHA), it necessary to use a relatively long period supplements such Ginkgo biloba extract (over several months) I thought you. In addition, dementia improvement action by turmeric, curcumin has also been reported. In DHC, also it has a product of complex supplements.

Cognitive function maintenance effect of PQQ (pyrroloquinoline quinone)

News field of economic paper (bulletin), "Pebbles and food, tofu development of DHC and for women." There was heading. (2015/6/7 23:30 Nihon Keizai Shimbun electronic edition) This is the news about the product handled by the convenience store of poplar and community store. The tofu of Tabekiri size, is to set the seasoning of olive oil, also contains hyaluronic acid there is a beautiful skin effect as a functional component. It is a private tail study diary today. PQQ is the abbreviation of pyrrolo quinoline quinone, about 10 years ago, the study of a new vitamin is reported, it has been attracting attention. (It should be noted, PQQ itself have been found already in the 1970s, from the action of the PQQ of metabolism, has been shown before about data 10 years that meet the definition of a vitamin, it is history that. Then, with respect to basic research and clinical significance, various discussions have been made. ) Currently, PQQ, in animals and plants, and to act as a growth factor, the metabolism of molecules in transcription factors and in mitochondria such as PPARα, has been found to be related to energy metabolism, such as the promotion of β-oxidation. Also, In the basic research using rats and mice, PQQ (300㎍ / kg ~ 3mg / kg dose) positive impact on growth and reproductive ability of, Such as a protective effect on ischemic state is shown. RIKEN of presentation materials of 2003, it will be seen in the following. For the first time in half a century new vitamin PQQ (pyrroloquinoline quinone) (It will link to the PDF file.) Well, it is a little previous research, Professional journal of nutrition, basic research that showed cognitive function maintenance effect of PQQ, has been reported from a group of Shibaura Institute of Technology. (J Clin Biochem Nutr 2008 Jan; 42:. 29-34.) In this study, Effects on learning and memory ability of PQQ and coenzyme Q10 (CoQ10) has been verified. In particular, Using rat, One of the PQQ or CoQ10 is administered, Evaluation of cognitive function related indicators have been made. First, In the early stages of the Morris water maze test, PQQ administration group, showed excellent learning ability than CoQ10 administration group. As for learning, PQQ + CoQ10 combination group showed improvement of about the same as PQQ administration group, no significant difference was found between the two groups. Then, In the second half of the Morris water maze test, PQQ administration group, CoQ10 administration group, PQQ + CoQ10 combination group, both showed improvement effect of the same degree of learning ability. In addition, In after oxidative stress load of 48 hours, PQQ + CoQ10 combination group, Compared to the control group, It shows a significant improvement effect of storage capacity. (In the PQQ + CoQ10 combination group, significant improvement for the memory impairment caused by oxidative stress has been found to be.) Other, In the study using vitamin E-deficient rats, By the administration of PQQ or CoQ10, but improvement of memory ability in oxidative stress load it has been shown, Storage capacity, and the PQQ administration group than CoQ10 administration group, is that was being maintained. From the above data, For the failure of neuropathy / storage ability of oxidative stress, Independent paths to the antioxidant action of vitamin E, Neuroprotective effect of PQQ, cognitive function (memory function) are suggested protective effect. In the future, it is the field of verification of clinical significance is expected. DHC has commercialized the PQQ-containing supplements. PQQ + Q10 Japan's first, new ingredients! To clean and dull was youthfulness

Cognitive by PQQ dysfunction inhibitory effect

Professional journal of the month of brain science research, had been reported basic research shows the neuroprotective effect of PQQ. (Behav Brain Res 2014 Jan 1; 258:. 153-9) Vitamin which is one PQQ (pyrroloquinoline quinone) of (like substance) is, and energy metabolism in the mitochondria, from a role in nerve function, Function to cognitive function has been suggested, Currently, the function of the brain as food has been appeal. In previous research, It has been suggested that PQQ binds to the NMDA receptor. In this study, Action by the PQQ in neurocognitive impairment has been verified. In particular, MK-801-induced abnormal behavior is a model of schizophrenia, in cognitive impairment model mouse, MK-801 (0.5mg / kg / d) When PQQ (0.2, 2.0, or 20 μg / kg / d) But 60 days, it is administered, Motor nerve capacity, have been made to evaluate, such as cognitive function test. As a result of the analysis, By PQQ administration, Behavioral abnormalities and ataxia of MK-801 induced significantly suppressed, Protective effect against neurological disorders and mental psychological behavioral abnormality is that has been suggested. In the future, it is the field of verification of clinical significance is expected. With respect to PQQ, subsequent studies have been reported. Anti-inflammatory effect of PQQ (pyrroloquinoline quinone): human clinical research Cognitive function maintenance effect of PQQ (pyrroloquinoline quinone)

Peripheral symptom improvement effect of dementia by Ginkgo biloba extract: a systematic review

Today, from Hachinohe Medical Association, 40th Hachinohe Medical Association of record collection has arrived. The end of last year, as a special lecture, the clinical significance and proper use of information supplements, such as question-and-answer session at the time when I was allowed to talk has been listed. Hachinohe Medical Association officials of everyone, Thank you. Well, it is a private tail study diary today. Professional journal of neuropsychiatric biology, systematic review was to verify the usefulness for the symptoms of dementia by Ginkgo biloba extract, it had been reported from the Swiss group (Centre Hospitalier Universitaire Vaudois). (World J Biol Psychiatry 2015 Jul 30:. 1-12) The Ginkgo biloba extract, there are specific flavonoid phytochemicals, antioxidant and anti-inflammatory effects, such as via the platelet aggregating action, and effective. So far, a number of clinical studies have been conducted, it has been shown efficacy and safety with respect to such as dementia. (And dementia improvement effect of Ginkgo biloba extract @ Germany) (Efficacy and safety of Ginkgo biloba extract) (And cognitive decline inhibitory effect by ingestion ginkgo leaf extract for 20 years) (Synergies with ginkgo biloba extract dementia therapeutic agent) Well, in this study, Ginkgo biloba extract supplements (EGb 761) by the administration Action to peripheral symptoms associated with dementia (behavioral and psychological symptoms (BPSD)) has been verified. In dementia, the core symptoms and peripheral symptoms (= BPSD) is seen. As a peripheral symptoms / behavioral and psychological symptoms (BPSD), And behavioral symptoms:. Violence, verbal abuse, wandering, rejection, such as filthy act And psychological symptoms: depression, anxiety, hallucinations, delusions, and sleep disorders. In particular, In patients with BPSD in dementia As a randomized placebo-controlled trials, 22 weeks or more, was administered the ginkgo leaf extract supplements (EGb 761), As an outcome, Measure the BPSD, Other, test the index were examined, such as cognitive function and ADL has been extracted. From randomized controlled trials 4 Report, Moderate dementia patients 1,628 people became the subject of analysis from mild. As a result of the analysis, The ginkgo biloba extract administration, Compared with the previous administration, Cognitive function, it is that BPSD, ADL, that has been found significant improvement in indicators such as CGI. (P <0.001 for all comparisons) From this review, The peripheral symptoms BPSD associated with Alzheimer's disease and vascular dementia, Ginkgo biloba extract supplements per day 240mg (EGb) is I will be considered valid. In DHC, there is a supplement of the following. 30 days ginkgo leaf It promotes the smooth flow, "health value and carelessly" measures! Normal price \ 810 (tax included \ 874) 3 grains total weight ginkgo leaf day (= Contents) per 900mg Ginkgo biloba extract powder (24% flavonoids, terpene lactones 6%) 180mg, niacin 8.8mg, pantothenic acid 3mg, vitamin B6 0.9mg, vitamin B2 0.7mg, Vitamin B1 0.7mg Saezae Comprehensive support dull in six components work in a complex manner Normal price \ 1,334 (including tax \ 1,440) Saezae the 1st 2 tablets total weight 1,010mg (Contents 660mg) per egg yolk oil (25% lecithin) 150mg, the end of Ginkgo biloba extract (24% flavonoids, terpene lactones 6%) 50mg, phosphatidylserine 40mg, GABA 10mg, DHA103 .5mg, EPA13.5mg PS (phosphatidylserine) 30 days It is supplemented with "brain nutrients", in daily without knowing "accidentally" Normal price \ 2,460 (tax) PS (phosphatidylserine) the 1st 2 tablets total weight 860mg (Contents 560mg) per DHA140mg, EPA18mg, phosphatidylserine 110mg Among the functional food supplement, the by human clinical studies, has been shown to dementia improvement action is the next component. - Ginkgo biloba extract Symptom improvement effect of dementia by ginkgo biloba extract formulation The dementia improvement effect of Ginkgo biloba extract @ Germany Efficacy and safety of ginkgo biloba extract The cognitive decline inhibitory effect by ginkgo biloba extract 20-year intake · PS (phosphatidylserine) supplements Cognitive function improving action by the PS (phosphatidylserine) Extra virgin (virgin) olive oil The dementia prevention effect of extra virgin olive oil Vitamin B group Brain atrophy due to vitamin B group administration (gray matter atrophy) inhibitory effect and cognitive decline inhibitory effect Clinical studies showed brain atrophy progression inhibitory effect Generally, when to expect the effect on cognitive function, B vitamins, omega-3 fatty acids (EPA and DHA), it necessary to use a relatively long period supplements such Ginkgo biloba extract (over several months) I thought you. In addition, dementia improvement action by turmeric, curcumin has also been reported. In DHC, also it has a product of complex supplements.